CONCLUSION : NMCM hydrogel can advertise chondrocytes proliferation , down regulate chondrocyte catabolism , baulk oxidative stress , protect chondrocytes from gristle harm , and promote cartilage repair.Quarternized chitosan/quercetin/polyacrylamide semi-interpenetrating network hydrogel with recoverability , toughness and antibacterial properties for wound healing.Antibiotic ill-usage has presented tremendous encumbrances on patients and healthcare systems