Non Prescription ADHD Medication The drugs for ADHD can help improve concentration, decrease hyperactivity and impulsive behavior. However, they do not work for everyone. They also have adverse effects and can lead to the risk of addiction. Clonidine (Catapres and Kapvay), Atomoxetine(Strattera)and guanfacine(Intuniv) are all non-stimulant options.