Best ADHD Medication For Adults Stimulant ADHD medication helps to improve the brain's ability to reduce the effects of symptoms such as hyperactivity poor focus and indecisiveness. There are many different stimulant medications that can be utilized to treat ADHD like methylphenidate (Ritalin), Concerta, Daytrana, Focalin and Adderall. Bupropion Bupropion