The Best Medicine For Anxiety Disorders SSRIs (selective serotonin reuptake inhibitors) and SNRIs such as citalopram (Celexa), escitalopram (Lexapro) and fluoxetine (Prozac) duloxetine (Cymbalta) and venlafaxine (Effexor XR) are considered the first-line drug treatments for anxiety disorders. Exercise and psychotherapy are essential for those suffering from anxiety. Some doctors prescribe