Best ADHD Medication For Adults Stimulant ADHD medication helps to improve the brain's function to lower the severity of symptoms such as hyperactivity poor focus and indecisiveness. There are many different stimulant medications that can be utilized to treat ADHD like methylphenidate (Ritalin), Concerta, Daytrana, Focalin and Adderall. Bupropion Bupropion