ADHD Treatment Medication Treatment for ADHD for adults usually involves psychosocial therapy and medication. Medications used to treat ADHD include stimulants and nonstimulant medications. Stimulants like methylphenidate or Lisdexamfetamine work on brain chemical messengers to boost mood, concentration, and impulse control. Atomoxetine and guanfacine are nonstimulant ADHD medications that can