Post Laser Hyperpigmentation - Melasma & dark skin Fundamentals Explained Postinflammatory hyperpigmentation can accompany different illness procedures that affect the skin. Check Here For More include allergies, infections, trauma, and phototoxic eruptions. Fractional laser photothermolysis sometimes causes postinflammatory hyperpigmentation. [5, 6] Common inflammatory illness that result in postinflammatory hyperpigmentation include