Non Prescription ADHD Medication Medications for ADHD can improve concentration and lessen impulse-driven and hyperactive behavior, but they don't work for everyone. These medications can also trigger side effects and addiction. Clonidine (Catapres and Kapvay), Atomoxetine(Strattera)and guanfacine(Intuniv) are all non-stimulant alternatives. These are known as alpha agonists